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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANLN All Species: 17.88
Human Site: S189 Identified Species: 35.76
UniProt: Q9NQW6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQW6 NP_061155.2 1124 124199 S189 S P P R P L L S N A S A T P V
Chimpanzee Pan troglodytes XP_001169875 1125 124324 S189 S P P K P L L S N A S A T P V
Rhesus Macaque Macaca mulatta XP_001103129 1127 124400 S189 S P P K P P L S N A S A A P V
Dog Lupus familis XP_539518 1121 123493 S189 S S P K P P L S D A S A T P V
Cat Felis silvestris
Mouse Mus musculus Q8K298 1121 122775 S187 S P S K P P I S N A S A T P V
Rat Rattus norvegicus XP_225479 975 107264 A97 S S A S G P S A S I N S S S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418836 1121 123757 D185 P P K Q A T N D L A S G T P I
Frog Xenopus laevis Q801E2 1116 122812 R188 G N D T P V G R R G R F A N L
Zebra Danio Brachydanio rerio NP_001096146 1153 127336 P214 L D H P P A T P T N S E V P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4P1 1239 136015 S274 K W D P K V L S S L E A Q G F
Honey Bee Apis mellifera XP_624050 1031 115155 D153 S T I N N W E D D L S H P T L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795668 1146 126808 E217 K A S M L Q R E P S G K V G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.9 87.8 N.A. 80.3 70.3 N.A. N.A. 63.6 56.4 49 N.A. 23.3 25 N.A. 24.7
Protein Similarity: 100 99.6 98.1 92.1 N.A. 87.1 77.1 N.A. N.A. 77.3 71.7 66.3 N.A. 42.7 44.4 N.A. 43.2
P-Site Identity: 100 93.3 80 73.3 N.A. 73.3 13.3 N.A. N.A. 33.3 6.6 26.6 N.A. 20 13.3 N.A. 0
P-Site Similarity: 100 100 86.6 86.6 N.A. 86.6 46.6 N.A. N.A. 46.6 20 26.6 N.A. 33.3 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 9 9 0 9 0 50 0 50 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 17 0 0 0 0 17 17 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 9 9 0 0 9 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % F
% Gly: 9 0 0 0 9 0 9 0 0 9 9 9 0 17 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 9 0 0 0 9 0 0 9 0 0 0 0 9 % I
% Lys: 17 0 9 34 9 0 0 0 0 0 0 9 0 0 0 % K
% Leu: 9 0 0 0 9 17 42 0 9 17 0 0 0 0 17 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 9 9 0 9 0 34 9 9 0 0 9 0 % N
% Pro: 9 42 34 17 59 34 0 9 9 0 0 0 9 59 0 % P
% Gln: 0 0 0 9 0 9 0 0 0 0 0 0 9 0 0 % Q
% Arg: 0 0 0 9 0 0 9 9 9 0 9 0 0 0 0 % R
% Ser: 59 17 17 9 0 0 9 50 17 9 67 9 9 9 0 % S
% Thr: 0 9 0 9 0 9 9 0 9 0 0 0 42 9 9 % T
% Val: 0 0 0 0 0 17 0 0 0 0 0 0 17 0 59 % V
% Trp: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _